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Compound Discovery

We are looking for a skilled technician to join our team to help with the discovery and identification of novel metabolites.


In this role, you will facilitate the discovery and identification of novel metabolites and support our vision to discover solutions to global issues, including the discovery of new antibiotics against resistant bacteria and fungicides to help global food security. You will have exposure to our company pipeline which spans from microbe isolation from soil through to compound structure elucidation. We will provide training in high-throughput screening, liquid handling automation, data analysis, and much more. In return, we are looking for open-minded, interdisciplinary scientists to accelerate our compound discovery efforts.


Our compound discovery team consists of analytical chemists and microbiologists who work closely with bioinformaticians and data scientists to collect the highest quality data for analysis. Together, we have built a database and bioinformatics pipeline that have informed our experiments to culture over 1,800 previously unexplored microbial species. Our compound discovery team work on characterising the novel compounds these microbes produce using liquid handling robotics, design of experiment procedures and fermentation techniques. 


Bactobio has over 300 sqm of laboratory space with high-end equipment spanning microbiology through to analytical chemistry. Within compound discovery, this includes a dedicated analytical chemistry suite with multiple mass spectrometers, HPLCs and high-throughput plate readers, as well as an automation suite with bioreactors, a flow cytometer and liquid handling machines.


  • Validation of hits through high throughput screening assays

  • Supporting the screening platform of microbial isolates for hit generation

  • Preparation of samples across the pipeline, driving throughput

  • Supporting the compound discovery team in the discovery and identification of novel metabolites

  • Ownership of project(s) and upskilling in various areas of the Bactobio pipeline

You should have:

  • A Master’s degree or above in chemistry or life sciences, or a BSc in chemistry or life sciences plus equivalent experience

  • Experience in culturing a range of microbes with good aseptic practice

  • Experience running liquid or solid bioassays on reporter strains

  • Experience in extraction methods for metabolites

  • Interest in biotechnology and enthusiasm for scientific discovery

  • Ability to work independently as well as within a team

It would be great if you have: 

  • Experience working in industry

  • Experience in analytical techniques for the separation of small molecules or proteins

  • Background in natural product chemistry

Benefits include:

  • Competitive starting salary

  • Brand new, modern labs in Central London with dedicated office space, large balconies and 360’ views of the London skyline

  • 25 days holiday + bank holidays

  • Diverse team of colleagues (check out our website to meet us)

  • Weekly team activities including board games, sports activities, and socials on Fridays

  • Complimentary breakfast, fruit, tea, coffee, snacks, drinks,...

  • Access to 1000s of training courses through Udemy, with an allowance for both personal development and work-related training

  • Opportunity to use your skills to help shape our innovative platform

Are you interested in joining us?
Send us your CV and an introductory paragraph using the link below

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