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We use next generation sequencing

to understand which microbes grow together

We use next generation sequencing to understand which microbes grow together

Genomics (NGS)

We use Design of Experiments (DoE) in conjunction with automation and data science to understand microbial communities

We use Design of Experiments (DoE) in conjunction with automation and data science to understand microbial communities

DoE/Automation

We use synthetic biology to isolate and grow our new microbes in the laboratory

We use synthetic biology to isolate and grow our new microbes in the laboratory

Synthetic Biology

MICROBIAL GENERATION PLATFORM

Microbes grow in complex communities

There are 10.000 microbial species in a gram of soil. These microbes grow in parallel micro-communities that have specific growth requirements

RESULTS

We have cultured over 800 new microbial species

Our microbes constitute 5% of all microbial species ever cultured and exist in new pockets of genetic and chemical space

Bactobio’s microbial collection

World culture collections

Bactobio’s microbial collection

World culture collections

We use DNA sequencing, machine learning,
and synthetic biology to culture novel microbes

We screen our novel microbes for chemicals that make the world greener and safer

We use bioinformatics, among other things, to identify which of our microbes have the highest chance of producing novel antimicrobials that target a specified pathogen

We use bioinformatics, among other things, to identify which of our microbes have the highest chance of producing novel antimicrobials that target a specified pathogen

Bioinformatics

We use molecular chemistry to build sensitive and miniaturised assays that we automate for high throughput

We use molecular chemistry to build sensitive and miniaturised assays that we automate for high throughput

Screening

We use analytical chemistry and chemoinformatics to efficiently identify the responsible antimicrobial compound

We use analytical chemistry and chemoinformatics to efficiently identify the responsible antimicrobial compound

Chemoinformatics

DISCOVERY PLATFORM

Our novel microbes are screened for novel antimicrobials against human & plant diseases

Each novel microbe produces thousands of compounds – most of these compounds have no known function or commercial potential. We have developed a pipeline to quickly identify novel chemistry with real-world impact

If you want to work with us please

RESULTS

We accept projects based on impact and can find antimicrobials targeting any human/plant microbial pathogen

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