
We use AI, DNA sequencing, and synthetic biology to culture novel microbial species
We screen our novel microbes for new classes of antimicrobials that are safe, effective, and bypass resistance

AI at Bactobio
The Challenge
Organic chemistry offers near-infinite configurations. Evolution optimizes for the best solutions - but gaining access to these solutions is complex and the data is noisy
Our Platform & Impact
We unlock substantial new areas of nature and control the data generation from soil to compounds
Our strong data focus means our agentic AI model Fleming can steer discovery - compressing timelines from decades to months
By optimizing and recombining these new chemistries, we deliver the next generation of safe, effective, and biodegradable products built for global impact

MICROBIAL GENERATION PLATFORM
Microbes grow in micro-communities
There are 10.000 microbial species in a gram of soil. Each microbe is dependent on their specific micro-communities and have specific growth requirements
We use next generation sequencing and wetlab experiments to generate data on which microbes grow together under which condition
We use next generation sequencing and wetlab experiments to generate data on which microbes grow together under which condition



Genomics (NGS)
We use AI, Design of Experiments (DoE), and automation to understand how microbial communities grow
We use AI, Design of Experiments (DoE), and automation to understand how microbial communities grow



DoE/Automation
Synthetic Biology drives our evolutionary process from community culturing to single species cultivation
Synthetic Biology drives our evolutionary process from community culturing to single species cultivation


Synthetic Biology

RESULTS
We have uniquely cultured over 4000 new species
Our microbial species constitute 20% of all species ever cultured
Bactobio’s microbial collection
World culture collections

Bactobio’s microbial collection
World culture collections
AI and bioinformatics identifies new species with the highest chance of producing novel antimicrobials with global impact
AI and bioinformatics identifies new species with the highest chance of producing novel antimicrobials with global impact



Bioinformatics
We use molecular chemistry to build sensitive and miniaturised assays that we automate for high throughput
We use molecular chemistry to build sensitive and miniaturised assays that we automate for high throughput



Screening
AI and chemoinformatics quickly identifies the responsible antimicrobial chemical structures
AI and chemoinformatics quickly identifies the responsible antimicrobial chemical structures



Chemoinformatics
DISCOVERY PLATFORM
Our novel microbes are screened for novel antimicrobials against human & plant diseases
Each novel microbe produces thousands of compounds – most of these compounds have no commercial potential. We quickly identifies novel chemistries with global impact
RESULTS
We accept projects based on impact and can find antimicrobials targeting any human/plant microbial pathogen
If you want to work with us please